0716 Quality of Life in Idiopathic REM Sleep Behavior Disorder and Isolated REM Sleep Without Atonia

Abstract Introduction Idiopathic rapid eye movement (REM) sleep behavior disorder (iRBD) can affect quality of life (QOL) for both patient and bed partner; isolated REM without atonia (iRSWA) has been less well-studied. We aimed to investigate whether QOL changes over time in those with either iRBD or iRSWA, as well compare these one another. Additionally, we attempted demonstrate certain were associated phenoconversion neurodegenerative illness. Methods prospectively analyzed data from the “REM Sleep Behavior Disorder Associations Parkinson’s Disease Study (RAPiDS)” cohort at baseline then follow-up evaluations. utilized Neuro-QOL self-reported questionnaire ascertain subjects’ level QOL. Results There 6 iRSWA 33 iRBD, an average age 61.9 ± 13.0 years, 13 women 26 men. Significant found group. Among who phenoconverted, fatigue social functioning main issues that worsened time. Conclusion This is first studied iRSWA. be affected conditions; seem particular importance they may phenoconversion. Support (if any) Grant a private individual